If benzyl alcohol is listed as a preservative for the Heparin preparation, do not use in neonates and infants or nursing mothers. Because of possible physical incompatibilities, SOLU-MEDROL should not be diluted or mixed with other solutions. Because of possible physical incompatibilities, SOLU-MEDROL should not be diluted or mixed with other solutions. Some drugs for injection may be incompatible in a given vehicle, or when combined in the same vehicle or in a vehicle containing benzyl alcohol. DOSAGE AND ADMINISTRATION. Intravenous administration of benzyl alcohol has been associated with serious adverse events and death in neonates (gasping syndrome). Benzyl alcohol, a preservative in Bacteriostatic Sodium Chloride Injection, USP has been associated with toxicity in neonates. Avoid injections containing benzyl alcohol in neonates (in neonates); dehydration; history of asthma; history of confirmed or suspected cerebrovascular bleeding; history of haemorrhagic diathesis; hypovolaemia; operations with high risk of haemorrhage DOSAGE AND ADMINISTRATION. Systemic exposure to benzyl alcohol has been associated with serious adverse reactions and death in neonates and low birth-weight infants when administered intravenously. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. Monitor for hyperkalemia (possibly from aldosterone suppression); mainly a concern among patients with risk factors including renal dysfunction, concomitant use of potassium sparing diuretics or potassium supplements Multidose formulation contains benzyl alcohol preservative, linked to fatal "gasping syndrome" in premature neonates. With in-depth features, Expatica brings the international community closer together. Benzyl Alcohol, 1.5%, is present as a preservative. However, adverse reactions have occurred in premature neonates and low birth weight infants who received intravenously administered benzyl alcohol-containing drugs {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. However, in neonates or very small infants the volume of fluid may affect fluid and electrolyte balance. With intravenous use: Sign Up DOSAGE AND ADMINISTRATION. Use in Neonates This product contains the preservative benzyl alcohol and is not recommended for use in neonates. Multidose vial contains benzyl alcoholmanufacturer advises avoid. Serious and fatal adverse reactions including gasping syndrome can occur in neonates and infants treated with benzyl alcohol-preserved drugs, including AquaMEPHYTON. Vials contain benzyl alcoholmanufacturer advises avoid. Systemic exposure to benzyl alcohol has been associated with serious adverse reactions and death in neonates and low birth-weight infants when administered intravenously. Intravenous administration of benzyl alcohol has been associated with serious adverse events and death in neonates (gasping syndrome). Geriatric Use. Data are unavailable on the toxicity of other preservatives in this age group. Drug Interactions. Benzyl alcohol has been reported to be associated with a fetal "Gasping Syndrome" in premature infants. Monitor for hyperkalemia (possibly from aldosterone suppression); mainly a concern among patients with risk factors including renal dysfunction, concomitant use of potassium sparing diuretics or potassium supplements Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. With intravenous use: Hydrochloric acid and/or sodium hydroxide may have been added during manufacture to adjust the pH (range 4.5-7.0). Use benzyl alcohol-free formulations in neonates and infants, if available. SOLU-MEDROL Sterile Powder is an anti-inflammatory glucocorticoid, which contains methylprednisolone sodium succinate as the active ingredient. Parenteral preparations containing benzyl alcohol should not be used in epidural or spinal anesthetic procedures. Hydrochloric acid and/or sodium hydroxide may have been added during manufacture to adjust the pH (range 4.5-7.0). Benzyl alcohol, a preservative in Bacteriostatic Sodium Chloride Injection, USP has been associated with toxicity in neonates. Some drugs for injection may be incompatible in a given vehicle, or when combined in the same vehicle or in a vehicle containing benzyl alcohol. Drug Interactions. NOTE: Some of the SOLU-MEDROL formulations contain benzyl alcohol (see DESCRIPTION, WARNINGS and PRECAUTIONS, Pediatric Use). Breast feeding Breast feeding For dalteparin sodium. Liquid solutions containing benzyl alcohol (including LEUKINE Injection) or LEUKINE for Injection reconstituted with Bacteriostatic Water for Injection, USP (0.9% benzyl alcohol) should not be administered to neonates and low birth weight infants. Data are unavailable on the toxicity of other preservatives in this age group. Warning in section 4.4 Benzyl alcohol is an aromatic alcohol with the formula C 6 H 5 CH 2 OH. For Intravenous or Intramuscular Administration . A must-read for English-speaking expatriates and internationals across Europe, Expatica provides a tailored local news service and essential information on living, working, and moving to your country of choice. Liquid solutions containing benzyl alcohol (including LEUKINE Injection) or LEUKINE for Injection reconstituted with Bacteriostatic Water for Injection, USP (0.9% benzyl alcohol) should not be administered to neonates and low birth weight infants. Multidose vial contains benzyl alcoholmanufacturer advises avoid. The formulations containing benzyl alcohol should not be used in neonates. Cautions Cautions For clindamycin. Benzyl Alcohol, 1.5%, is present as a preservative. Avoid injections containing benzyl alcohol in neonates (in neonates); dehydration; history of asthma; history of confirmed or suspected cerebrovascular bleeding; history of haemorrhagic diathesis; hypovolaemia; operations with high risk of haemorrhage However, adverse reactions have occurred in premature neonates and low birth weight infants who received intravenously administered benzyl alcohol-containing drugs Avoid injections containing benzyl alcohol in neonates (in neonates); dehydration; history of asthma; history of confirmed or suspected cerebrovascular bleeding; history of haemorrhagic diathesis; hypovolaemia; operations with high risk of haemorrhage Breast feeding Breast feeding For dalteparin sodium. A must-read for English-speaking expatriates and internationals across Europe, Expatica provides a tailored local news service and essential information on living, working, and moving to your country of choice. With intravenous use. Benzyl alcohol as a preservative in Bacteriostatic Sodium Chloride Injection has been associated with toxicity in newborns. Consult with pharmacist, if available. Consult with pharmacist, if available. SOLU-MEDROL Sterile Powder is an anti-inflammatory glucocorticoid, which contains methylprednisolone sodium succinate as the active ingredient. Drug Interactions. Natroba Topical Suspension contains benzyl alcohol and is not recommended for use in neonates and infants below the age of 6 months. Use in Neonates This product contains the preservative benzyl alcohol and is not recommended for use in neonates. Benzyl alcohol has been reported to be associated with a fetal "Gasping Syndrome" in premature infants. Multidose formulation contains benzyl alcohol preservative, linked to fatal "gasping syndrome" in premature neonates. Data are unavailable on the toxicity of other preservatives in this age group. Monitor liver and renal function in neonates and infants. Benzyl alcohol as a preservative in Bacteriostatic Sodium Chloride Injection has been associated with toxicity in newborns. Acute psychosis; adrenogenital syndrome; allergic disorders; asthma; avoid injections containing benzyl alcohol in neonates; Cushing's syndrome; infectious diseases; peptic ulcer; primary adrenocortical insufficiency; refractory heart failure. Cautions Cautions For tetracosactide. 5.2 Risk of Serious Adverse Reaction in Infants due to Benzyl Alcohol Preservative . For Intravenous or Intramuscular Administration . If preparations without benzyl alcohol are used in pediatric patients, the initial dose is usually 50 units per Kg but a Some drugs for injection may be incompatible in a given vehicle, or when combined in the same vehicle or in a vehicle containing benzyl alcohol. Cyanocobalamin: Benzyl alcohol has been associated with toxicity (gasping syndrome) in neonates; each mL of cyanocobalamin injection (e.g., preparation manufacturered by Abraxis) contains 15 mg of benzyl alcohol. Sign Up DESCRIPTION . (0.9% benzyl alcohol) should not be administered to neonates and low birth weight infants. Data are unavailable on the toxicity of other preservatives in this age group. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. The formulations containing benzyl alcohol should not be used in neonates. Warnings. Cautions Cautions For clindamycin. Because of possible physical incompatibilities, SOLU-MEDROL should not be diluted or mixed with other solutions. Breast feeding Due to the relatively high molecular weight of tinzaparin and inactivation in the gastro-intestinal tract, passage into breast-milk and absorption by the nursing infant are likely to The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. DESCRIPTION . Benzyl alcohol is an aromatic alcohol with the formula C 6 H 5 CH 2 OH. However, adverse reactions have occurred in premature neonates and low birth weight infants who received intravenously administered benzyl alcohol-containing drugs Benzyl alcohol, a preservative in the multiple-dose vial preparations of Heparin Lock Flush Solution, USP has been associated with toxicity in neonates. Benzyl Alcohol, 1.5%, is present as a preservative. Benzyl alcohol, a preservative in Bacteriostatic Sodium Chloride Injection, USP has been associated with toxicity in neonates. Monitor liver and renal function in neonates and infants. Acute psychosis; adrenogenital syndrome; allergic disorders; asthma; avoid injections containing benzyl alcohol in neonates; Cushing's syndrome; infectious diseases; peptic ulcer; primary adrenocortical insufficiency; refractory heart failure. With intravenous use: SOLU-MEDROL Sterile Powder is an anti-inflammatory glucocorticoid, which contains methylprednisolone sodium succinate as the active ingredient. Multidose vial contains benzyl alcoholmanufacturer advises avoid. Vials contain benzyl alcoholmanufacturer advises avoid. Multidose vial contains benzyl alcoholmanufacturer advises avoid. Serious and fatal adverse reactions including gasping syndrome can occur in neonates and infants treated with benzyl alcohol-preserved drugs, including AquaMEPHYTON. If preparations without benzyl alcohol are used in pediatric patients, the initial dose is usually 50 units per Kg but a Warning in section 4.4 5.2 Risk of Serious Adverse Reaction in Infants due to Benzyl Alcohol Preservative . Warning in section 4.4 A must-read for English-speaking expatriates and internationals across Europe, Expatica provides a tailored local news service and essential information on living, working, and moving to your country of choice. Cautions Cautions For tetracosactide. The minimum amount of benzyl alcohol at which toxicity may occur is not known. Avoid injections containing benzyl alcohol in neonates (in neonates); diarrhoeal states. Benzyl alcohol has been reported to be associated with a fetal "Gasping Syndrome" in premature infants. Directions for administration Directions for administration For clindamycin. If benzyl alcohol is listed as a preservative for the Heparin preparation, do not use in neonates and infants or nursing mothers. However, in neonates or very small infants the volume of fluid may affect fluid and electrolyte balance. Ferrlecit contains benzyl alcohol as a preservative; because benzyl alcohol is rapidly metabolized by a pregnant woman, benzyl alcohol exposure in fetus is unlikely. Directions for administration Directions for administration For clindamycin. Warnings. With in-depth features, Expatica brings the international community closer together. Use in Neonates This product contains the preservative benzyl alcohol and is not recommended for use in neonates. Data are unavailable on the toxicity of other preservatives in this age group. Sign Up Liquid solutions containing benzyl alcohol (including LEUKINE Injection) or LEUKINE for Injection reconstituted with Bacteriostatic Water for Injection, USP (0.9% benzyl alcohol) should not be administered to neonates and low birth weight infants. Hydrochloric acid and/or sodium hydroxide may have been added during manufacture to adjust the pH (range 4.5-7.0). 5.2 Risk of Serious Adverse Reaction in Infants due to Benzyl Alcohol Preservative . Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. Data are unavailable on the toxicity of other preservatives in this age group. NOTE: Some of the SOLU-MEDROL formulations contain benzyl alcohol (see DESCRIPTION, WARNINGS and PRECAUTIONS, Pediatric Use). Data are unavailable on the toxicity of other preservatives in this age group. If benzyl alcohol is listed as a preservative for the Heparin preparation, do not use in neonates and infants or nursing mothers. Consult with pharmacist, if available. Benzyl alcohol, a preservative in the multiple-dose vial preparations of Heparin Lock Flush Solution, USP has been associated with toxicity in neonates. There have been reports of fatal gasping syndrome in neonates (children less than one month of age) following the administration of intravenous solutions containing the preservative benzyl alcohol. Geriatric Use. Warnings. Geriatric Use. Avoid injections containing benzyl alcohol in neonates (in neonates); diarrhoeal states. The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Monitor for hyperkalemia (possibly from aldosterone suppression); mainly a concern among patients with risk factors including renal dysfunction, concomitant use of potassium sparing diuretics or potassium supplements The formulations containing benzyl alcohol should not be used in neonates. Parenteral preparations containing benzyl alcohol should not be used in epidural or spinal anesthetic procedures. There have been reports of fatal gasping syndrome in neonates (children less than one month of age) following the administration of intravenous solutions containing the preservative benzyl alcohol. Ferrlecit contains benzyl alcohol as a preservative; because benzyl alcohol is rapidly metabolized by a pregnant woman, benzyl alcohol exposure in fetus is unlikely. Breast feeding Breast feeding For dalteparin sodium. Acute psychosis; adrenogenital syndrome; allergic disorders; asthma; avoid injections containing benzyl alcohol in neonates; Cushing's syndrome; infectious diseases; peptic ulcer; primary adrenocortical insufficiency; refractory heart failure. (0.9% benzyl alcohol) should not be administered to neonates and low birth weight infants. There have been reports of fatal gasping syndrome in neonates (children less than one month of age) following the administration of intravenous solutions containing the preservative benzyl alcohol. Benzyl alcohol, a preservative in the multiple-dose vial preparations of Heparin Lock Flush Solution, USP has been associated with toxicity in neonates. Methylprednisolone Multidose vial contains benzyl alcoholmanufacturer advises avoid. Avoid injections containing benzyl alcohol in neonates (in neonates); diarrhoeal states. Cautions Cautions For clindamycin. With intravenous use. Serious and fatal adverse reactions including gasping syndrome can occur in neonates and infants treated with benzyl alcohol-preserved drugs, including AquaMEPHYTON. Breast feeding Due to the relatively high molecular weight of tinzaparin and inactivation in the gastro-intestinal tract, passage into breast-milk and absorption by the nursing infant are likely to Breast feeding Due to the relatively high molecular weight and inactivation in the gastro-intestinal tract, passage into breast-milk and absorption by the nursing infant are likely to Methylprednisolone Vials contain benzyl alcoholmanufacturer advises avoid. However, in neonates or very small infants the volume of fluid may affect fluid and electrolyte balance. Expatica is the international communitys online home away from home. Parenteral preparations containing benzyl alcohol should not be used in epidural or spinal anesthetic procedures. Benzyl alcohol as a preservative in Bacteriostatic Sodium Chloride Injection has been associated with toxicity in newborns. The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Data are unavailable on the toxicity of other preservatives in this age group. For Intravenous or Intramuscular Administration . With in-depth features, Expatica brings the international community closer together. Cautions Cautions For tetracosactide. Expatica is the international communitys online home away from home. Directions for administration Directions for administration For clindamycin. With intravenous use. Breast feeding Due to the relatively high molecular weight and inactivation in the gastro-intestinal tract, passage into breast-milk and absorption by the nursing infant are likely to Multidose formulation contains benzyl alcohol preservative, linked to fatal "gasping syndrome" in premature neonates. Multidose vial contains benzyl alcoholmanufacturer advises avoid. Benzyl alcohol as a preservative in Bacteriostatic Sodium Chloride Injection has been associated with toxicity in newborns. Data are unavailable on the toxicity of other preservatives in this age group. NOTE: Some of the SOLU-MEDROL formulations contain benzyl alcohol (see DESCRIPTION, WARNINGS and PRECAUTIONS, Pediatric Use). Methylprednisolone Benzyl alcohol as a preservative in Bacteriostatic Sodium Chloride Injection has been associated with toxicity in newborns. Benzyl alcohol is an aromatic alcohol with the formula C 6 H 5 CH 2 OH. If preparations without benzyl alcohol are used in pediatric patients, the initial dose is usually 50 units per Kg but a Data are unavailable on the toxicity of other preservatives in this age group. Ferrlecit contains benzyl alcohol as a preservative; because benzyl alcohol is rapidly metabolized by a pregnant woman, benzyl alcohol exposure in fetus is unlikely. Natroba Topical Suspension contains benzyl alcohol and is not recommended for use in neonates and infants below the age of 6 months. Natroba Topical Suspension contains benzyl alcohol and is not recommended for use in neonates and infants below the age of 6 months. Use benzyl alcohol-free formulations in neonates and infants, if available.